Monday, November 1, 2010

Drainage:

The ability of the suspension to break cleanly away from the inner walls of the primary containe4r closure system is another important characteristic of well formulated parenteral suspension. Completely peptized to flocculated systems show this property, while over flocculated systems exhibit some degree of poor drainage. The process of silicone coating of containers, vials and plugs with dimethicone makes good suspensions drain better and helps reverse the tendency toward poor drainage by slightly over flocculated systems.

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