Processing of preparing injectable suspensions:

Processing of preparing injectable suspensions:

Aseptically dispensing the sterile, milled active ingredient (s) into a sterile vehicle system, milling the resulting suspension as necessary and filling the milled suspension into suitable sterile containers.
Solubilizing the active ingredient (s) in a suitable solvent system, adding a sterile vehicle system or counter solvent system that causes the active ingredient (s) to crystallize, aseptically removing the organic solvent; milling the resulting suspension as necessary and the milled suspension into suitable containers.
If the suspensions requires milling, then it is reticulated for a period of time through the colloid mill to ensure complete dispersion.