Monday, November 1, 2010

Rheology:

The rheological behavior of a pharmaceutical suspension furnishes the greatest control over sedimentation and optimization of the physical stability of the system. The choice of the rheology is depends on the type of bodying agent and its intended application.
For more viscous medium → a bodying agent is not necessary to increase the viscosity.
For less viscous medium → a bodying agent is necessary to increase the viscosity.

For example - for a topical suspension:
It should be fluid enough to permit proper shaking and pourability
Should not flow readily form the skin
Should provide sufficient resistance against gravitational settling while in the container

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